CELL2007 Molecular Exploration Project
Group 7
Representative Proteins
 Homo-sapiens TESK1TESK1 isoform 2 from Homo-sapiens |  Tongue SoleTESK1 from Cynoglossus semilaevis (Tongue Sole) |  Wild Bactrian CamelTESK1 from Camelus ferus (Wild Bactrian Camel) |  Chinese HamsterTESK1 from Cricetulus griseus (Chinese hamster) |
|---|---|---|---|
 ZebrafishTESK1 from Danio rerio (Zebrafish) |  Homo-sapiens TESK2TESK2 from Homo-sapiens |  Red JunglefowlTESK1 from Gallus Gallus (Red Junglefowl) |  MouseTESK1 from Mus musculus (Mouse) |
 Norwegian RatTESK1 Rattus norvegicus (Norwegian rat) |  DogTESK1 from Canis lupus familiaris (Dog) |  CowTESK1 from Bos Taurus (Cow) |  Rhesus MacaqueTESK1 from Macaca mulatta (Rhesus macaque) |
 ChimpanzeeTESK1 from Pan troglodytes (Chimpanzee) |
Representative Proteins are shown with descriptions together with flat file hyperlinks when clicked. There is less information on computationally predicted sequences from genomic analysis. The TESK1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and zebrafish [2].
Figure 3 : Phylogenetic tree for TESK1. It can be seen that TESK1 (isoforms 1 and 2) from Homo sapiens and TESK1 from Mus musculus have the most sequence identity, and are in fact more closely related to TESK2 from Homo sapiens and R. norvegicus than TESK1 from species such as G. gallus and D. rerio. TESK1 from birds and fish seem to be closely related, whereas mammals are less so. Phylogenetic analysis also showed that TESK1 is closely related to LIMK.